科学美国人:First Benefit of Knowing Your Genome

60秒科学节目(SSS)是科学美国人网站的一套广播栏目,英文名称:Scientific American - 60 Second Science,节目内容以科学报道为主,节目仅一分钟的时间,主要对当今的科学技术新发展作以简明、通俗的介绍,对于科学的发展如何影响人们的生活环境、健康状况及科学技术,提供了大量简明易懂的阐释。

“I think if genome sequencing gets just super cheap then it’s… probably very soon going to make sense to just sequence all your DNA.”

Science journalist Carl Zimmer, author of the book She Has Her Mother’s Laugh: The Powers, Perversions and Potential of Heredity. Zimmer spoke last month at New York University’s Journalism Institute. Right now, commercial genome services only look at a small percentage of all your DNA. But as the cost plummets, you’ll get your entire genome. 

“Then the issue will become, well, what do you use your genome for in terms of your health. A lot of people will actually benefit from something I learned by looking at my genome, which is, that if God forbid I were to get hepatitis there are certain drugs that won’t do me any good. Because I have certain genes. Pharmacogenomics, as it’s called. I think that pharmacogenomics might be kind of the low-hanging fruit of genome sequencing. Because, doctors so often, if you get sick, they’re like, well, let’s try this. It might be hepatitis, it might be depression, all sorts of things, like, well, that didn’t work very well, let’s try this. Wouldn’t it be nice if we could just skip the stuff that doesn’t work and go to the stuff that does? So that might be kind of where medicine goes in terms of using our genomes and understanding how heredity affects your health.”

—Steve Mirsky

(The above text is a transcript of this podcast)  

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